2022 Slideshow: Top 500 US Manufacturing Companies with Highest Profits
In the realm of U.S. manufacturing, the search for the top 500 companies with high profit margins in 2022 yields no direct results. However, a closer look at specific sectors reveals promising indicators of profitability.
Semiconductor manufacturing, particularly chipmakers in the U.S., have been noteworthy for strong revenue and profit margins recently. Visual Capitalist's 2025 report highlights America's top chipmakers by revenue, profit margins, and growth, which likely includes companies with high profit margins in 2022 as well.
Oil refining companies in the U.S. Midwest also experienced relatively high profit margins through early 2022. Refining margins stayed positive due to strong oil prices, especially for certain types like WCS ex-Cushing coking.
While broader industrial production data from the Federal Reserve covers manufacturing output and capacity utilization, it does not directly identify highly profitable companies. Additionally, the Conference Board's leading economic indicators track manufacturing orders and economic conditions but do not list companies or profit margins specifically.
To identify the actual top 500 U.S. manufacturing companies by profit margin in 2022, one would typically refer to detailed financial databases or commercial ranking lists like Forbes, Fortune, or S&P Global industry reports. These lists often select companies based on annual financial filings and segment by industry.
For a more precise ranking by profit margin, consulting commercial financial data providers or specialized business intelligence platforms would be necessary. If your goal is to gain insights into the profitability of specific manufacturing niches, examining profits as a proportion of sales can be particularly useful. High sales totals are significant, but profit margin is a valuable metric for evaluating fiscal performance.
In the coming months, the 2023 list for the U.S. 500 manufacturing companies will be unveiled, potentially bringing significant changes. Until then, a slideshow focusing on the financial performance of the U.S. manufacturing sector offers a representation of the current state.
Notable performers from the U.S. manufacturing sector included Texas Instruments Inc., Microsoft Corp., Hologic Inc., DuPont de Nemours Inc., Cooper Companies Inc., Nvidia Corp., Quidel Corp., Bio-Rad Laboratories Inc., SPX Corp., and Regeneron Pharmaceuticals Inc. Among these, two companies had profit exceeding sales.
The data provided for these companies is from Seeking Alpha and S&P Global. This slideshow serves as a snapshot of the U.S. manufacturing sector's financial performance in or around 2022, with semiconductor manufacturers and Midwest oil refiners standing out as sectors with notably high profit margins.
- In the realm of technology, semiconductor manufacturers like Texas Instruments Inc. and Nvidia Corp., which were highlighted in a slideshow, have shown notable high profit margins in 2022.
- For those interested in personal-finance and investing, examining the financial performance of companies in the gadgets sector, such as Microsoft Corp., would provide insights into their profitability, given their high profit margins.
- In addition to semiconductor manufacturing and oil refining, companies in the business sector like DuPont de Nemours Inc. and Regeneron Pharmaceuticals Inc., renowned for their high profit margins, can be opportunities for smartphone manufacturers to learn about profit optimization strategies in their respective domains.
